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EFdA (Islatravir): An Outstanding Anti-HIV Modified Nucleoside

EFdA(4’-C-ethynyl-2-fluoro-2’-deoxyadenosine), named Islatravir by Merck, is a very excellent anti-HIV modified nucleoside. The story of its development, especially the basis of its design, advances in its synthetic methods, amazing clinical results and unexpected clinical results, and further, the possibility of EFdA as the clinical medicine, is described.

ISBN: 979-8-89248-176-2

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ISBN

979-8-89248-176-2

Author

Hiroshi Ohrui

Publisher

Publication year

Language

Number of pages

67

Description

EFdA(4’-C-ethynyl-2-fluoro-2’-deoxyadenosine), named Islatravir by Merck, is a very excellent anti-HIV modified nucleoside. The story of its development, especially the basis of its design, advances in its synthetic methods, amazing clinical results and unexpected clinical results, and further, the possibility of EFdA as the clinical medicine, is described.