Link between D-dimer, COVID-19 and acute ischemic stroke

Description

Ischemic stroke is an acute neurological disease caused by vascular occlusion. It is one of the leading causes of death and disability worldwide and is caused by a combination of environmental and genetic factors. Latest in the wake of the SARS-COV-2 (Severe Acute Respiratory Syndrome coronavirus 2) pandemic, COVID-19 disease, named as Corona Virus Infectious Disease-19 by World Health Organization was involved in the development of this condition. Several factors might explain the association of the COVID-19 disease and increased acute ischemic stroke risk. Meanwhile, previous studies reported that D-dimer may be common causative factors for COVID-19 and acute ischemic stroke but there is still no clear evidence for an association between D-dimer, COVID-19 disease and acute ischemic stroke. I performed a subgroup analysis based on the level of D-dimer and the possible association of the level of D-dimer with the appearance of the two diseases to further understand the importance of high level of D-dimer.